Fatty meal interrupts gut's communication with the body, but why?

Gut cells that normally tell the brain and the rest of the body what's going on after a meal shut down completely for a few hours after a high-fat meal, a team of researchers discovered in zebrafish. Enteroendocrine cells normally produce at least 15 different hormones to send signals to the rest of the body. The finding could be a clue to insulin resistance that leads to Type 2 diabetes.